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Soreness, tongue irritation, and difficulty chewing are some of the early signs of oral cancer

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Some extreme anxiety never did

For instance, the participants were interviewed several decades ago so it was uncertain whether their tobacco habits had changed during the follow-up period (how many snus users had switched to smoking?) Other problems were the select nature of the participants and the failure to control for other significant life style factors, including alcohol consumption and dietary habits

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Some experts argued that smoking increases testosterone secretion, which might increase the risk of developing prostate cancer